Kidney stone combined with hyperuricemia medication is divided into two aspects. Kidney stone treatment includes non-surgical therapy (lithotripsy, litholytic therapy) and surgical therapy, commonly used oral drugs such as tamsulosin, etc. Hyperuricemia treatment includes alkalinization of urine and uric acid-lowering therapy, etc., commonly used oral drugs such as bicarbonate of soda tablets, allopurinol, phenylbromarone, febuxostat, etc. Kidney stones: including lithotripsy and litholytic therapy, less than 0.5cm stones, most of them can be discharged by drinking water, appropriate activities, assisted with some lithotripsy drugs such as tamsulosin, etc. 1.0cm or more stones, the treatment mostly adopts surgical therapy. Litholytic therapy is used for uric acid stones and cystine stones, alkalinization of urine is the key, commonly used drugs are sodium bicarbonate tablets, potassium citrate and so on. Hyperuricemia: including alkalinization of urine and uric acid lowering treatment. The former commonly used drugs include sodium bicarbonate tablets, etc. The latter drugs include allopurinol, benzbromarone, febuxostat, etc. The choice of drugs should be used under the guidance of physicians. When kidney stones are combined with hyperuricemia, you should go to the hospital in time and choose the appropriate treatment plan under the guidance of a professional doctor.