The main treatments for knee osteoarthritis are conservative treatment, medication and surgery. 1. Conservative treatment: Reduce weight bearing on the joints as well as high-intensity exercise, obese patients should reduce their weight so as to lower the load on the joints and reduce the wear and tear pressure on the joints, and crutches can also be used to assist walking and reduce the pressure. 2. Medication: After risk assessment, anti-inflammatory and analgesic drugs, such as NSAID celecoxib, can be used. Cartilage protectors, such as glucosamine sulfate, can also be used to relieve symptoms in patients with knee osteoarthritis. 3. Surgery: For patients with advanced osteoarthritis of the knee, if they are able to tolerate surgery, it is recommended that they undergo knee replacement, which is currently recognized as the most effective treatment option for pain, deformity, and function, and is very effective in restoring the functionality of the patient’s knee joint. Osteoarthritis of the knee is recommended to choose the appropriate treatment under the guidance of a doctor, the above drugs should be used under the guidance of a doctor.