Repeated fever with high C-reactive protein suggests that there may be acute tissue injury, inflammation and infection, acute rheumatic immune disease and other causes, and timely consultation is needed. 1. Acute tissue injury: including severe trauma, post-surgery, acute myocardial infarction and other causes. 2. Inflammatory infections: mostly caused by bacterial infections, common infectious bacteria include Staphylococcus aureus, Streptococcus pneumoniae, etc., which can cause acute infections such as pneumonia and septicemia. 3. Acute rheumatic immune diseases: acute rheumatoid arthritis, systemic lupus erythematosus and other diseases will also appear different degrees of fever and high C-reactive protein. Repeated fever with high C-reactive protein, it is recommended to go to the hospital in a timely manner, to clarify the cause of the disease, and for the specific cause of treatment.