Segmental motion abnormality of the left ventricular wall is generally due to coronary heart disease myocardial infarction caused by necrosis of cardiomyocytes, and cardiomyocytes belong to the terminally differentiated cells, once damaged necrosis can not be regenerated, the necrotic cardiomyocytes in the area of myocardial infarction by the proliferation of fibroblasts to replace the fibroblasts do not have cardiomyocyte contraction ability, due to the segmental motion abnormality of the wall can not be restored. When the segmental motion abnormality of the left ventricular wall occurs, the patient should be highly suspected of having a previous or current myocardial infarction, and according to the patient’s symptoms and signs and improve the relevant examination, if the diagnosis of existing myocardial infarction, then we should go to the hospital as soon as possible, and then carry out coronary artery revascularization to improve the ischemia at an early stage to save the residual cardiomyocytes, and combine with medication in the postoperative period, in order to slow down the remodeling of the myocardium and to prevent the occurrence of serious adverse events.