In the case of a soft growth on the buttocks, the condition may be a cyst in the subcutaneous tissue of the area. The most common types of cysts are mucous cysts under the skin, or sebaceous cysts. It is also possible that the area of subcutaneous tumors, mainly benign tumors, the most common may be lipoma, or lipocystic tumors. Of course, there may also be an infection in the area, especially due to localized suppurative infection, when the production of pus may be soft, but then there may be pus, need to be incised to drain pus treatment. When dealing with this tenderness, the first thing that needs to be determined is whether or not an infection is present. If there is an infection, aggressive anti-infection treatment is needed, and only after the inflammation subsides can surgical excision be performed.