Usually, there are many hazards of staying up late for a long time, such as skin diseases, eye diseases, obesity and so on. 1. Skin diseases: long-term stay up late, the human body can not get enough rest, will affect the metabolism of the organs, will be manifested from the skin, resulting in skin pimples, acne, but also produce wrinkles, pigmentation, the skin will become drier. 2. Eye diseases: long stay up late, the eyes can not get enough rest, will lead to temporary vision loss, if often overnight will lead to blurred vision, conjunctival congestion. 3. Obesity: people will secrete growth hormone during sleep, which can help the body break down fat, if you stay up late for a long time, it will lead to hormone secretion disorders, so that the accumulation of fat, thus appearing overweight and obesity. In addition, long-term stay up late can also appear other hazards, such as feeling unwell, it is recommended to go to the hospital in a timely manner, follow the doctor’s instructions for treatment.