Perianal abscesses with pus can usually be treated with medication and surgery. If the perianal abscess is mild, you can choose medication, and if there is a serious reaction of rupture, surgical treatment is needed. 1. Medication: medication mainly includes amoxicillin, cefepime, ibuprofen, acetaminophen, naproxen, etc. It is mainly applied to abscesses with mild symptoms, and can play the role of symptomatic antipyretic, anti-inflammatory and analgesic. 2. Surgical treatment: (1) abscess incision and drainage: mainly for most of the perianal abscess, the pus, infected necrotic tissue removal and adequate drainage of pus, to avoid undrained abscess to continue to expand, as well as the progress of extensive systemic infection. (2) fistulotomy: the purpose is to prevent the existence of anal fistula, perianal abscess recurrence possibility, according to the specific circumstances of the disease at the same time with other surgery for treatment. If the perianal abscess pus, it is recommended to go to the hospital in time for the relevant examination, under the guidance of a professional doctor to carry out the appropriate treatment.