Fever is a problem that pediatricians encounter every day, and although it is easy to handle, what are the safe medications recommended by the WHO? What is the correct treatment? Do you know all these questions? Fever is a problem pediatricians encounter every day and should be handled with ease, but I never thought there would be so much controversy over such a simple issue. The first time I realized this was in a WeChat group. One day I was invited to enter a pediatrician’s group, and we were discussing how to reduce fever. Some people said to use Merlin, others said to use small herbs. I thought what was there to discuss about such a simple issue, so I hurriedly typed a line: WHO recommends acetaminophen and ibuprofen as safe and effective fever-reducing drugs. Just sent out, immediately attracted a meal of questions and objections, some people said that eating antipyretic drugs is not good, or injections to come quickly, the best effect of analgesic antipyretic; some people said that the first choice to reduce high fever dexamethasone; some people said that the side effects of Western medicine, Chinese medicine Chaihu antipyretic good; some people said analgesic plus dexamethasone enema, what kind of high fever can be retired, the effect is good and not suffer. The more I read, the more surprised I was, I was anxious but didn’t know what to do. I wanted to popularize the knowledge of science and advocate the correct concept of medication, but when I saw them arguing in the heat of the day, hey, forget it, I’d better back off! For fever highlights the following points: 1, fever is a protective response of the body, is a self-protective mechanism against pathogenic microorganisms formed during the long evolutionary process. 2, whether antipyretic treatment needs to weigh the pros and cons. 3.Safe and effective antipyretic drugs are acetaminophen and ibuprofen, and fever-reducing injections such as Advil and lysergic acid are unsafe, and the application of glucocorticoids for fever reduction is strongly opposed. 4, physical cooling can be used as an auxiliary antipyretic method, warm water baths can be used, alcohol baths, ice packs to cool down, ice water enemas should not be used. 5. Prophylactic application of antibacterial agents is not advocated. In conclusion, a certain degree of fever is beneficial to people, and whether or not cooling treatment is needed depends on how the child feels. It is important to keep in mind that the purpose of fever reduction is to improve the child’s comfort and reduce the child’s irritability and discomfort caused by fever. Reducing fever does not shorten the course of the fever, and excessive cooling is not conducive to recovery from the disease. Oral antipyretic drugs are safer and should be the first choice when fever reduction is needed. The efficacy of physical cooling alone is limited and is no longer recommended. The use of glucocorticoids such as dexamethasone to reduce fever is prohibited, fever-reducing injections are also unsafe, and antimicrobials should not be abused.