Cranial defects are a relatively common disorder in neurosurgery and are often encountered in clinical practice. Cranial defects generally occur after surgical treatment of traumatic brain injury, cerebral hemorrhage, brain tumor and a small number of cerebral infarction and other cranio-cerebral diseases, and are usually left behind due to decompression of combined high cranial pressure and debridement. Due to the high incidence of various accidents and unintentional injuries in recent years, as well as the high incidence of various cranio-cerebral diseases, the incidence of cranial defects has also been higher in recent years. As we know, the skull is a solid barrier to protect the safety of the brain and maintain the health of the body, if the skull defect occurs, it is quite dangerous and harmful, and it will be a great threat in terms of safety, health and aesthetics. For example, many patients with cranial defects will have different manifestations of cranial defect syndrome. So what are the manifestations of cranial defect syndrome? The manifestation of craniosynostosis syndrome has various forms, specifically dizziness and headache, unfavorable limbs, numbness and weakness, low mood, irritability, irritability, unexplained discomfort and various mental disorders, some patients may have impaired vision, hearing impairment, lack of smell and other symptoms, and more serious may have epileptic seizures. These manifestations of craniosynostosis can cause great disturbance to the life and work of patients. Of course, in addition to cranial defect syndrome, there are also threats to safety, external injuries may directly harm the brain tissue, and even endanger life; there are also cosmetic anomalies, the patient’s skull appearance is very unattractive, may receive the same eyes of the outside world; there is also a psychological blow, some patients have low self-esteem, feel that the lack of skull, they are not the same as others, some people even feel like a semi-disabled And so on. Therefore, skull repair surgery is needed in time after skull defect, through skull repair plastic surgery, it can rebuild a complete closed cranial environment for patients, which can largely alleviate and improve the skull defect syndrome, and also help patients to regain their psychological confidence and resume normal working life again.