Fat milk needs to be infused daily and if it is infused every few days, it is not conducive to the nutritional support of the organism. Fat milk is a parenteral nutrition preparation that provides the body with essential fats. Fat milk is usually used in patients who cannot eat normally or cannot be supported nutritionally and is usually infused daily to meet the patient’s daily fat or energy needs. The amount of daily infusion needs to be calculated according to the amount required by the patient, which requires the judgment of the specialist to calculate the amount of fat milk needed in combination with the energy required by the patient and other nutritional support agents, such as glucose, amino acids and other nutritional preparations. Patients with long-term fatty milk infusion should pay attention to fat excretion and liver function. Weekly blood picture, blood coagulation and sedimentation tests are recommended, and treatment should be promptly administered if the tests are abnormal.