LDL is a major risk factor for atherosclerosis, which can be reduced to below 1.8mmol/L by lifestyle modification and medication such as statins, intestinal CH absorption inhibitors, Probucol, bile acid sequestering agents and other drugs.
1. Lifestyle modification: dyslipidemia is obviously affected by diet and lifestyle, LDL can be lowered through dietary control such as limiting the intake of saturated fatty acids, supplementing soluble dietary fiber, quitting smoking, quitting alcohol, limiting salt, etc.; it can also be achieved by increasing exercise and maintaining 30 minutes of moderate-intensity metabolic exercise every day.
2. Statin drugs: statin drugs can up-regulate the cell surface LDL receptor, accelerate its catabolism and significantly reduce LDL, common drugs include atorvastatin, simvastatin, resuvastatin, etc.
3. Intestinal CH absorption inhibitors: common drugs for ezetimibe, can act in the small intestine cells, inhibit cholesterol absorption, can reduce LDL.
4. Probucol: it can penetrate into the core of LDL particles to affect lipoprotein metabolism and promote the clearance of LDL.
5. Bile acid chelator: it can block the intestinal and hepatic circulation of bile acid, so that the bile acid is discharged with feces, reducing the absorption of LDL, and it can be used in combination with statin drugs to significantly reduce LDL.
When dyslipidemia occurs, you need to choose the optimal program under the guidance of a professional doctor to use medication.