Cholinesterase 14000 is often referred to as cholinesterase 14000 U/L in clinical practice, and whether it is serious or not requires reference to its assay. There are two methods of testing serum cholinesterase, including colorimetric and enzymatic methods. If the colorimetric method detects cholinesterase 14000U/L, it is a high result and more serious. If the enzymatic method detects cholinesterase 14000 U/L, it is not serious because the normal range of the enzymatic method is wide and cholinesterase 14000 U/L basically falls within the normal range. Clinically elevated cholinesterase can be seen in neurological disorders, hyperthyroidism, hypertension, diabetes, hyperlipoproteinemia, bronchial asthma, renal failure, and other diseases. Low cholinesterase indicates poor synthetic function of the liver and can be seen in diseases such as poor liver function, hepatitis, cirrhosis, organophosphorus poisoning, malnutrition, and myocardial infarction. When abnormal cholinesterase indexes are found during physical examination, you should go to the hospital promptly and generally need to combine with other diseases or tests to clarify the cause and confirm the disease. If there are other common chronic diseases or liver diseases, it is recommended to review the indexes regularly and follow up regularly.