Patients always wake up in the middle of the night to consider the following reasons: 1, to consider may be related to the patient’s psychological factors, patients who have long-term mental stress, work more nervous, resulting in emotional anxiety, it is easy to appear in the middle of the night when the sleep is not deep, easy to appear in the middle of the night always wake up; 2, to consider may be caused by some disease factors, patients who have problems with gastroduodenal ulcer, it is easy to In the middle of the night there are episodes of stomach pain, which in turn will affect the patient’s sleep; patients always wake up in the middle of the night is related to neurological weakness, in this case need to be adjusted by some drugs, patients should also adjust their own lifestyle, to develop good habits.