The most common symptom of lymphoma is painless and progressive enlargement of superficial lymph nodes, mostly in the neck, armpits and groin. Patients often do not care about it, and as the disease progresses, they often visit the hospital with a lump in the neck that grows larger and larger without pain, and in advanced stages, multiple enlarged lymph nodes fuse with each other to form a mass. Since the lymphatic tissue spreads throughout the body, cough, shortness of breath, chest tightness, pleural effusion; abdominal pain, abdominal mass, ascites, hepatomegaly, splenomegaly, jaundice; skin itching, bone pain, lower limb paralysis, etc. can occur. Systemic symptoms are characterized by prolonged recurrent fever with malaise, excessive sweating and wasting. Since the clinical manifestations are very complex and varied, it is extremely easy to misdiagnose the disease. Therefore, the possibility of lymphoma should be thought of in patients with painless and progressive enlargement of lymph nodes of unknown origin or recurrent fever.