Small hard bumps on the skin under the scrotum may be related to epididymal inflammation, scabies nodules, sebaceous cysts, folliculitis and other diseases, and the treatment should be chosen according to different causes, such as medication, liquid nitrogen freezing, surgical treatment and so on. 1. Inflammation of epididymis: mostly caused by viral and bacterial infections, patients can be treated with drugs such as levofloxacin, ibuprofen and acetaminophen. If the drug treatment does not see obvious results, you can also choose surgery for incision and drainage to reduce the abscess. 2. Scabies nodules: Scabies nodules can appear in scrotum infected with scabies, which can be manifested as small bumps on the skin under the scrotum or accompanied by itching and pain. Patients can use tacrolimus ointment to apply externally, or inject tretinoin injection at the nodules to relieve itching, or use liquid nitrogen freezing, carbon dioxide laser and other methods of treatment. 3. Sebaceous cysts: the skin follicles at the scrotum are blocked, and the sebaceous glands can gather to form small bumps. You can use penicillin, cephalosporin and other antibiotic drugs for treatment, can also use cystectomy for surgical treatment. 4. Folliculitis: Bacterial infection of the hair follicles in the scrotum can lead to folliculitis, which can lead to small bumps on the skin. Fusidic acid cream and other drugs can be used for treatment, if the hair follicles appear abscess symptoms, may need surgery for incision and drainage. Small hard bumps on the skin under the scrotum can also be seen for other reasons. The patient should consult a doctor in time, after clarifying the cause of the disease, under the guidance of a professional doctor for standardized treatment.