The most common cause of blood vessel blockage refers to atherosclerosis-occlusive disease, and the main causes of atherosclerosis-occlusive disease are closely related to such diseases as hyperlipidemia, diabetes, and hypertension. The first thing to do is to control hyperlipidemia, control hypertension, and control diabetes, which may require corresponding control of lipids with statins, control of hypertension with antihypertensive drugs, and improvement of diabetes with insulin or other glucose-lowering drugs. On the basis of these basic treatments, local ischemia of the lower extremities still occurs, and interventional treatment can also be used to open the occluded narrowed blood vessels with guidewires, catheters, balloons, and stents to ensure blood supply to the tissues and organs in the vascular supply area, improve ischemic symptoms, and also restore the patient’s energy supply. Many patients have no problems with daily life and basic activities after these treatments.