Who is likely to be a high-risk candidate for erectile dysfunction (ED)? Are you a high-risk candidate for ED? Erectile dysfunction (ED) has always been a taboo subject for men. The fast-paced life and unbalanced diet structure of modern society have made more and more modern people prematurely involved with diabetes, hypertension, cardiovascular and cerebrovascular diseases. And ED and hypertension, diabetes and other closely related. A clinical survey shows that about 52% of hypertensive patients and 68% of diabetic patients have ED, and even many male and urological experts bluntly say: hypertension, diabetes patients are at high risk of ED; many patients with poorly controlled conditions, ED is a matter of time. The main reason why hypertension leads to ED is because of the arteriosclerosis caused by hypertension, which reduces blood flow to the lower body, thus affecting the blood supply to the penis, leading to or aggravating ED. In addition, because sex requires a certain amount of physical strength, some patients with severe or poorly controlled hypertension, will experience discomfort during sex, which also aggravates the patient’s fear of worsening hypertension during sex, coupled with the occasional failure of intercourse produces psychological barriers. The occurrence of ED is inevitable. Most of the inability to get an erection in diabetic patients also occurs gradually. At the same time, some of the drugs used to treat hypertension and diabetes may also lead to ED, and in recent years there has been a significant increase in the trend. Such as the action of the central anti-hypertensive drugs such as methyldopa, its inhibitory effect on sexual function is proportional to the amount of the drug, the daily dose is greater than or equal to 2 grams, there will be 50% of male patients with significant sexual dysfunction. Fortunately, ED complicated by diabetes and hypertension is completely treatable. When ED occurs in men with hypertension, phosphodiesterase (PDE5) inhibitor drugs are available. “In the treatment of ED, the first thing is to adhere to the treatment of the original disease, control blood pressure, and control the risk factors that lead to hypertension, such as weight loss, a reasonable diet, and avoid excessive emotions. If a patient develops ED after using a certain antihypertensive drug, consult a doctor to adjust or switch to another drug.” There are currently some drugs for hypertension, such as angiotensin II receptor antagonists, which themselves have a vasodilating effect and can also increase the blood supply to the penis when treating hypertension. The patient can consult with the doctor if these drugs can be used to effectively treat ED while treating hypertension. Diabetic ED also requires “management” of the primary lesion, including lifestyle modification, the application of oral hypoglycemic drugs and insulin, etc. PDE5 inhibitors are the first-line drugs for the treatment of diabetic ED. It can significantly improve symptoms and achieve and maintain a satisfactory erection. This drug is effective in both patients with poor glycemic control and those with severe co-morbidities. In addition, a proportion of patients with diabetic ED can be treated with both PDE5 inhibitors and oral testosterone with good results. Today there is a trend toward younger ED, so young and middle-aged men must be vigilant. The first step is to prevent the occurrence of high-risk diseases, such as hypertension and diabetes. Low sugar, low salt, low fat, high fiber, high vitamin, is the best diet combination to “defend” against these diseases. Regular monitoring of body weight to maintain it at normal levels is also essential. “In 1992, the International Heart Association introduced the ‘four cornerstones of health’, namely proper diet, moderate exercise, smoking cessation and alcohol restriction, and psychological balance, the core of which is a healthy lifestyle. While this is intended to reduce the incidence of hypertension, erectile function is, in the end, also a vascular issue, so these considerations apply just as much.”