Hematochezia after prostate puncture, which is caused by damage to the prostate, requires abstinence for about two weeks, along with oral antibiotics to prevent infection. Indications for prostate puncture biopsy include: (1) tPSA located in 4-10ng/ml, need to refer to the value of free PSA, if fPSA/tPSA is less than 0.16, need prostate puncture biopsy. (2) If tPSA ≥10ng/ml, prostatectomy biopsy is more necessary. (3) Imaging (ultrasound or MRI) reveals suspicious lesions. (4) Rectal examination reveals suspicious lesions in the prostate. As prostate puncture causes certain damage, it is easy to bleed after ejaculation after puncture, and it is necessary to abstain from sex for about two weeks, and take oral antibiotics as prescribed by the doctor to prevent infection, such as levofloxacin, cefixime, etc., and eat light food and drink more water to prevent constipation. Usually this kind of bleeding can be relieved within a week, if the symptoms are not obvious relief or even gradually aggravated, you need to go to the regular hospital for further consultation, to find out the cause of the disease and then give appropriate treatment.