Typical symptoms of mediastinal lymph node hyperplasia are often closely related to its location and the hyperplasia. Patients mainly present with chest tightness, shortness of breath, and in some cases, fever. Patients will present with persistent high fever, which is not effective on antibiotic treatment, along with chills. Severe cases of anemia, immunocompromised, patients hematopoietic function destruction, resulting in a decrease in red blood cells. Immunocompromise occurs. Respiratory distress may also complicate, leading to asphyxia. Some patients may be asymptomatic for a long time, and are diagnosed only when a mediastinal mass is found during physical examination or examination for other diseases, or when they visit the doctor for complications.1. Chest pain and tightness in the chest: the patient will have retrosternal pain, which will diffuse to the whole chest wall, accompanied by wheezing, and a feeling of tightness and swelling of the chest.2. Fever: the patient will have a persistent high fever, which is ineffective in the treatment of antibiotics, and is accompanied by chills.3. Anemia: the patient’s immunocompromised status will destroy the blood-forming function, resulting in a decrease in red blood cells. function is destroyed, resulting in a decrease in red blood cells and immunocompromise; 4. Difficulty in breathing: patients will experience autonomic dyspnea and inability to breathe when lymph nodes compress the airways.