Coldness below the knee may be the cause of thromboembolic vasculitis, atherosclerosis of the lower extremities, and polyarteritis, which can be treated with vasodilator drugs, aspirin combined with statins, and immunosuppressants, respectively.
1. Thromboembolic vasculitis: Thromboembolic vasculitis is a segmental inflammatory disease of blood vessels due to smoking, endocrine disorders, increased blood coagulation, etc. It is more common in the lower limbs, and due to ischemia of the lower limbs, it can be manifested as coldness, numbness and fatigue, and it can be treated by vasodilating drugs such as cilostazol and saxagrebate hydrochloride.
2. Lower extremity atherosclerosis: Lower extremity atherosclerosis is induced by long-term hypertension, high blood pressure, high blood cholesterol, resulting in insufficient blood supply to the lower extremities, symptoms of coldness, numbness, pain, can be applied to aspirin combined with statins to control the progression of atherosclerosis.
3. Polyarteritis: Polyarteritis is a chronic progressive inflammation of the aorta and its branches caused by unknown reasons, resulting in stenosis or occlusion of blood vessels, the descending aorta and abdominal aorta can cause numbness, coldness and pain in the lower limbs when they are involved, and can be treated with immunosuppressants such as methotrexate and cyclophosphamide.
If the symptoms of coldness below the knee, you need to go to the hospital in time to clarify the cause, the doctor according to the situation of the individualized treatment plan, any choice of drugs should be selected under the guidance of a professional doctor, do not use your own medication, in order to avoid delaying the condition.