Lipid deposition myopathy is a condition in which there is an abnormal amount of lipid deposition in the muscle and it is the predominant pathological change. It is a metabolic disorder caused by defects in the oxidation of long-chain fatty acids in muscle, and is a manifestation of inherited disorders of fat metabolism in the nervous system. Most patients with this disease have a family history of autosomal recessive inheritance. Lipid deposition myopathy is a manifestation of fat metabolism disorder involving skeletal muscle. This disease occurs more often in children, adults can also develop, most of the slow onset of the disease, mainly involved in the skeletal muscles, limbs are symmetrical muscle weakness, and even severe mild myasthenia. In addition, cervical muscles, chewing muscles, swallowing muscles and tongue muscles can be involved, the longer the muscle movement, the more pronounced weakness, and accompanied by muscle swelling and pain. The general course of the disease is from several months to several years, and it is a systemic disease, often accompanied by low ketogenic hypoglycemic symptoms.