Renal tubular injury is not the mildest kidney disease, there are many causes of renal tubular injury, and the severity of the condition varies according to the causes, which cannot be generalized. Renal tubular diseases are divided into primary and secondary, primary renal tubular diseases are mostly caused by hereditary reasons, secondary renal tubular diseases are caused by ischemia, drug intoxication or secondary to hypertension, autoimmune diseases and so on. The most frequent consequence of renal tubular disease is acidosis, which is a decrease in blood pH caused by renal tubular acidification dysfunction, leading to several metabolic dysfunctions that may have serious consequences if not treated in time. Patients with renal tubular injury are advised to visit regular hospitals in time for standardized examination and treatment under the guidance of physicians.