1, now many pregnant women have simple low FT4 blood, this need to be treated with drugs, will have an effect on the fetus? No, the guidelines do not support or oppose it. I personally use medication. 2. Can I supplement iodine for subclinical hypothyroidism in pregnancy? How much should be measured? Some patients with low T4 blood are caused by iodine deficiency, and they will be fine after iodine supplementation. If only TSH is elevated and urinary iodine is not a problem, iodine supplementation is needed, and even restriction of high iodine intake is needed. 3. How to treat TPO-Ab that is always high during pregnancy? What are the risks to pregnancy and fetus? There is no good treatment. In case of recurrent miscarriage or premature delivery, thyroid hormone treatment is recommended. 4, the fetus mainly uses FT4, why instead the regulation of tsh is stricter than FT4, simply low FT4, TSh is normal, instead of how aggressive treatment? In fact, elevated TSH represents a deficiency of thyroid hormone. The first manifestation of hypothyroidism is not a decrease in T4, but an increase in TSH, just like when an employee makes a mistake, the first person to react is his leader, when the thyroid gland makes a mistake, its supervisor, the pituitary gland, is immediately on high alert. The thyroid gland makes a mistake and its boss, the pituitary gland, is immediately on high alert, secreting TSH to make the thyroid gland work hard! 5, hypothyroid mothers need to take L-T4 after delivery, it is generally recommended to breastfeed every day before taking the medication, but how long is it appropriate to breastfeed again after taking the medication? (Worried about the higher T4 of the lotion inhibiting the TSH of the baby) Left thyroxine taken on an empty stomach or before bedtime, the best effect, the child can choose any time to breastfeed, long-term medication users, thyroid hormones have reached a dynamic balance, the milk concentration is relatively stable, do not separate, if it is hyperthyroidism is another story. 6. What is the effect of elevated TpOAb and TGAb during pregnancy on the pregnant woman and the fetus? Do they need to be controlled? How should they be controlled? No special treatment is needed, and there is no good way to lower the antibodies. The main risk is miscarriage and premature birth, but the incidence is not very high, so don’t worry. 7. If you have been suffering from hypothyroidism for 10 years and have been taking Eugenol for a long time, what should you pay special attention to when you get pregnant? Maintain normal thyroid function before you get pregnant, please refer to my reply to everyone to see what normal thyroid function means. If you are pregnant, you should consult your doctor immediately, review your thyroid function and adjust your medication dose. 8. Regarding the medication during pregnancy for hyperthyroidism patients, some people advocate different medication for the first 3 months and later, while others advocate using propylthiouracil all the time during pregnancy. If the original methimazole is used, it can be left unchanged. If not, it is recommended to start using PTU for three months, and if the patient uses PTU for a long time, there is no need to change it throughout pregnancy. Both drugs do not affect postpartum breastfeeding, and it is recommended to breastfeed 4 hours after taking the drug. 9. Eugenol is shocking for new onset hypothyroidism in pregnancy? Then how to grasp this starting dose? Is it based on nail function or weight? Or both? Can you provide a conversion formula? Whenever hypothyroidism is detected during pregnancy, the minimum starting dose is 50ug. If it is more severe, the starting dose can be as high as 1.7-2.0ug per kg of body weight. 10. How long can a woman with hypothyroidism treated with iodine 131 take Eugenol after long-term treatment and maintain normal thyroid function before considering pregnancy? How often is it appropriate to recheck the thyroid function during pregnancy? Is there a rough conversion formula between this dosage and body weight? What do you think about the suggestion that mothers taking Eugenol should not breastfeed? First question: you can get pregnant after six months of treatment with normal thyroid function; second: review 3-4 weeks in the beginning phase and extend the time later; third: dose adjustment needs to be increased by about 30-50%, there is no formula, it can only be determined according to the examination; fourth: it is definitely possible to breastfeed. It does not affect the child. 11. Is it right to treat hypothyroidism or subthyroidism diagnosed during pregnancy by L_T4, monitor normal thyroid function and use the medication until delivery? How to treat after delivery? The guidelines say to reduce the dosage to the pre-pregnancy medication level, but the patient did not use the medication before pregnancy, should we stop the medication directly or gradually reduce the dosage and stop it? That’s a good point! Always use the medication and stop after delivery, some women, not only do not have hypothyroidism after delivery, but will be mildly hyperthyroid. Do not discontinue the medication gradually, just stop it suddenly. Retest again about 6 weeks after delivery. 12.Patients with subclinical hypothyroidism in pregnancy diagnosed at an early stage, but with negative antibodies, no abnormalities in ultrasound and other related examinations, and normal previous thyroid function, do they need treatment? How to treat? How to stop the medication? To treat, use levothyroxine, starting with one tablet (50ug) per day and rechecking and adjusting in 3-4 weeks.