The first application of antidepressant drugs usually takes effect within 7-10 days, and 20 days to a month to show better effect, so the effect of antidepressant drugs usually takes effect in about a week, you may feel some changes in mood, your mood may be happier, your sleep has improved, you no longer have difficulty sleeping, your previous interests gradually start to recover, you start to want to communicate with people, you want to go out to study and work, which can all show that The medication is taking effect in the body, and generally the effects will have these feelings just now, which also prove that the medication is working. Therefore, it is necessary to go for regular follow-ups and adjust the dosage of medication according to the doctor’s prescription in time. It is not recommended to increase or decrease the medication abruptly because depression is a kind of mental illness that can be easily repeated.