Crush syndrome is a serious trauma. A series of pathophysiologic changes occur in the muscular part of the human body after sustained and prolonged extrusion of a heavy object, which causes a variety of clinical symptoms, i.e., the formation of compression syndrome. The main manifestations of crush syndrome are shock, myoglobinuria, acidosis and hyperkalemia. High blood potassium mainly comes from: muscle tissue necrosis, producing a large number of metabolic products, myoglobin, potassium ions, creatine. Acidosis promotes the transfer of potassium ions from intracellular to extracellular, resulting in a rapid rise in blood potassium. Hyperkalemia can be further aggravated by acute renal failure due to shock hypotension and renal ischemia, and renal potassium excretion dysfunction.