The cause of coronary artery calcification is still unclear, and it is associated with risk factors such as dyslipidemia, hypertension, smoking, etc. Treatment can be done with aspirin, statins, etc. as prescribed by the doctor. Coronary artery calcification is a manifestation of calcium deposition during coronary atherosclerosis, the cause of which is unclear, and is associated with risk factors such as older age, dyslipidemia, hypertension, smoking, diabetes mellitus and glucose intolerance. The treatment of coronary artery calcification includes general preventive and curative measures, medication, and surgery. 1. General preventive and curative measures include actively controlling related risk factors, such as smoking cessation, controlling hypertension, diabetes mellitus and other underlying diseases; secondly, reasonable diet, reducing fat and cholesterol intake, restricting alcohol consumption, appropriate exercise, and maintaining a good attitude. 2. Drug therapy can use antiplatelet drugs such as aspirin, clopidogrel, etc., as well as lipid regulators such as atorvastatin calcium tablets, fenofibrate, ezetimibe and so on. If blood clots form in the arteries, thrombolytic therapy can be performed with drugs such as streptokinase. 3. If the coronary artery is severely narrowed or even occluded, timely interventional therapy such as balloon dilatation, stent implantation can be performed to restore the blood supply, or bypass grafting surgery can be performed after the condition is stabilized. Coronary artery calcification, need to actively consult the doctor, follow the doctor’s instructions for reasonable treatment, drugs need to be rationally applied under the guidance of a physician.