The patient sleeps with swollen eyes, may be blepharitis, conjunctivitis, keratitis, etc., the patient can follow the doctor’s instructions to use medication, to promote the recovery of the condition. 1. blepharitis: the main symptom of blepharitis patients is the redness and swelling of the eyelids, patients can also appear eyelid pain, patients can follow the doctor’s instructions to use antibiotic medication, such as erythromycin ophthalmic ointment, levofloxacin eye drops, etc., to control the inflammation, and to promote the recovery of the condition. 2. Conjunctivitis: If allergic patients are allergic to the pillowcase, duvet cover and other allergies when sleeping, allergic conjunctivitis can appear after waking up with swollen eyes, patients can follow the doctor’s instructions to use sodium cromoglycate eye drops and other antiallergic drug treatment to promote recovery. 3. Keratitis: keratitis patients can appear vision loss, eyelid redness and swelling and other symptoms, the patient can follow the doctor’s instructions to use medication, such as tobramycin eye drops, ganciclovir ophthalmic gel, etc., to control the inflammation, promote the recovery of the condition. It is recommended that patients who wake up with swollen eyes should consult a doctor to evaluate their condition and follow the doctor’s instructions for treatment.