Amoxicillin and aspirin do not have conflicting drug components and can be taken together if the condition requires it and there are no contraindications. Amoxicillin belongs to a group of antibiotics that are used to treat respiratory infections, pneumonia, otitis media, acute sinusitis, nephritis, urethritis, skin and soft tissue infections. Possible side effects include allergic reactions, gastrointestinal reactions such as bloating, nausea, vomiting, abdominal distension, and diarrhea. Aspirin has the effect of inhibiting platelet aggregation and is used in the treatment of angina pectoris, myocardial infarction, cerebral infarction, and the prevention of deep vein thrombosis and pulmonary embolism after major surgery. Possible side effects include abdominal pain, dyspepsia, peptic ulcer, increased risk of bleeding, kidney injury, and allergic reactions. Contraindications to amoxicillin include hypersensitivity to the drug, the presence of severe hepatic impairment, and contraindication in patients with infectious mononucleosis and lymphocytic leukemia with bacterial infection. Contraindications to aspirin include hypersensitivity to aspirin or other salicylates, peptic ulcers, bleeding disorders, severe cardiac, hepatic and renal failure, and prohibition of combination with methotrexate. Amoxicillin and aspirin two drug ingredients do not conflict, and there is no clear provisions can not be combined, so the two in the condition of the need and no contraindications to the above drugs can be used together.