Hidden pain in the middle of the upper abdomen in the middle of the night mainly includes stomach diseases, intestinal diseases, pancreatic, gallbladder diseases, circulatory system diseases and so on. The upper abdomen of the human body contains the stomach, pancreas, bile ducts, transverse colon and other organs, usually the epigastric middle hidden pain originates from these parts. 1. Gastric diseases:When patients suffer from chronic gastritis, gastric ulcer and other diseases, the discomfort of pain in the middle of the upper abdomen will occur. 2. Intestinal diseases: patients suffering from chronic enteritis, transverse colon spasm, tumors and other diseases, will appear in the epigastric middle pain. 3. Pancreatic and gallbladder diseases: patients suffering from pancreatitis, cholecystitis and other diseases may have epigastric pain in the middle of the abdomen. 4. Circulatory system diseases: When patients suffer from diseases such as variant angina pectoris, epigastric pain may also occur. If the pain is frequent and difficult to relieve, it is recommended to go to the hospital for further examination to clarify the cause.