Psoriasis is a common and multi-infarct disease that endangers people’s physical and mental health. The number of psoriasis patients in China is on the rise, and according to statistics, it has reached 6.5 million people. Because psoriasis has a long course, is prone to recurrence and occurs on the surface of the body, which hinders aesthetics, many patients are under great psychological pressure and heavy mental burden. Some patients mistakenly believe that psoriasis is an incurable disease, and some people mistakenly believe that the disease is contagious and discriminate against patients. Therefore, the psychological pain of patients is often greater than the symptoms of their skin lesions. There are different misconceptions among the general public and patients. It is very important to maintain a good state of mind and knowledge of the disease. Many patients are under great psychological pressure after doctors diagnose them with psoriasis and are influenced by traditional concepts and public opinion, believing that they suffer from an incurable disease and are depressed and suppressed, which is not only detrimental to the remission and recovery of the disease, but can also aggravate the disease and make the treatment resistant. Patients are too pessimistic and their physical and mental health is in a state of disgusting cycle. The current psoriasis medical market is very confusing, all kinds of media and even in the streets and alleys of the treatment of psoriasis advertising overwhelming, abound, some “wandering doctor”, even not at all dermatologists, driven by economic interests, using the psychology of patients want to cure, claiming to be “experts “, “specializing in the treatment of psoriasis”, cheating patients and profiteering, causing a lot of physical and psychological injuries of medical origin and a huge economic burden to patients. Many psoriasis patients and their families are poor in knowledge about psoriasis, blindly pursue the root cure, gullibly believe in some advertising propaganda and throw themselves at doctors indiscriminately, and the phenomenon of aggravating the disease and even causing serious consequences by mis-treatment and drug abuse is quite serious. A survey conducted by the Institute of Dermatology of the Chinese Academy of Medical Sciences shows that 58.6% of the 320 psoriasis patients do not know about psoriasis, 8.6% consult doctors about the knowledge, 89% do not read the scientific knowledge of psoriasis, 24% believe that it can be cured, 72.6% believe in various advertisements and have received treatment from individual doctors. The percentage of those who have received treatment from individual doctors is 65.7%. Therefore, the prevention and control of psoriasis must strengthen the popular education of psoriasis-related knowledge, and regular medical treatment and good health education can make the condition improve or even cure. Patients should read more psoriasis science manuals, as well as have the guidance and follow-up of an experienced and conscientious specialist dermatologist.