The most common cause of burning pain in the thigh is lumbar disc herniation. After a lumbar disc herniation, it compresses the surrounding nerve roots and causes sensory dysfunction of the limbs, which can cause burning pain in the thighs. The second common cause is infection of the surrounding tissues. For example, there is a septic infection in the surrounding area. This causes peripheral pain with a burning sensation. The third common cause is the peripheral nerve. For example, in pear-shaped muscle syndrome, the pear-shaped muscle compresses the sciatic nerve and causes nerve symptoms, including a burning sensation in the thigh.