Late stage bowel cancer spreading abdominal pain can be treated symptomatically or causally by painkillers, radiotherapy and extraction of ascites. Bowel cancer is a more common malignant tumor, with colorectal cancer being more common, which can be caused by various factors such as gene mutation and heredity. When the disease develops to the late stage, it is often accompanied by distant metastasis, such as abdominal organ metastasis and peritoneal metastasis. At this time, abdominal pain, ascites, abdominal distension and other clinical manifestations may appear. Advanced patients can often take ibuprofen and other painkillers under the guidance of the doctor; can also be treated by radiotherapy, targeted therapy and other methods of treatment; for patients with severe ascites, abdominal puncture to extract ascites is also feasible symptomatic therapy. For patients with serious ascites, ascites extraction by abdominal puncture is also feasible. Patients can actively cooperate with doctors for treatment. Patients with advanced stage of intestinal cancer with spreading abdominal pain should seek medical treatment in time and under doctor’s guidance, so as to avoid delaying the condition.