The vast majority of cases of vaginal bleeding at 45 days of pregnancy are due to vaginal bleeding caused by genetic deletion of the embryo. This condition is clinically more likely to fail if the anamnesis treatment. Another cause of bleeding is due to trauma or after intercourse, which causes abruption between the chorion and the uterine wall. Absolute bed rest should be given clinically, and antirefetal treatment should be given according to the blood HCG and progesterone monitoring. Progesterone can be administered orally or intramuscularly, and hemostasis is given. During the period of medication, absolutely no more sexual intercourse is allowed, and rest and nutrition should be taken care of.