Sore throat and fever are common in acute tonsillitis, acute pharyngitis and other diseases, need to choose the targeted treatment according to the cause and symptoms, different through the symptoms to determine the medication. 1. Acute tonsillitis: mostly caused by B hemolytic streptococcus infection, the symptoms of sore throat and fever can occur. Sore throat or high fever, oral antipyretics and analgesics, such as acetaminophen. Penicillin antibiotics, such as amoxicillin, may be used depending on the type of causative organism. If the condition does not improve after 2-3 days of treatment, the cause should be analyzed and other types of antibiotics should be used. 2. Acute pharyngitis: may be caused by viral and bacterial infections, may also be secondary to acute rhinitis or acute tonsillitis, you need to take cephalosporin capsules, cefaclor capsules and other medications, such as accompanied by recurrent fevers, you can also use acetaminophen fever medication. Sore throat and fever need, according to the doctor’s guidance to improve the examination, clear cause and degree of illness, follow the doctor’s instructions for targeted medication and treatment.