Gastroesophageal reflux is the reflux of gastric contents into the esophagus, and its pathogenesis is related to abnormalities in the structure and function of the anti-reflux barrier, reduced esophageal clearance, and reduced barrier function of the esophageal mucosa.
1. Abnormalities in the structure and function of the anti-reflux barrier: Digestive diseases such as gastric dilatation, abdominal effusion, constipation, delayed gastric emptying, etc., or foods and drugs can cause abnormalities in the structure and function of the anti-reflux barrier, thus leading to gastroesophageal reflux.
2. Reduced esophageal clearance: mostly seen in diseases with abnormal esophageal peristalsis and reduced salivary secretion, such as desiccation syndrome.
3. Reduced barrier function of esophageal mucosa: e.g. long-term alcohol consumption, smoking, irritating foods or drugs.
In addition, poor dietary habits, obesity, etc. can also induce the occurrence of gastroesophageal reflux. Patients may experience symptoms of reflux and heartburn. In addition to standardized medication as prescribed by the doctor, daily attention should be paid to adjusting the lifestyle, such as proper exercise, weight reduction, and maintaining a comfortable mood, in order to alleviate the uncomfortable symptoms of acid reflux and heartburn.
It is recommended that patients with gastroesophageal reflux should go to the gastroenterology department of the hospital in a timely manner.