Raised hard lumps at the hand joints may be caused by tendon sheath cysts, lipomas, radial fractures, etc. They can be treated with medication (e.g., hydrocortisone acetate), surgery, and other treatments (e.g., manipulative repositioning). 1. Tendon sheath cysts: slow-growing cyst-like lumps will appear at the wrist joint. When the cysts persistently increase in size and discomfort occurs, the fluid can be extracted by puncture and hydrocortisone acetate can be injected, and then pressure bandage can be applied; recurrent cysts can be surgically removed; and the cyst fluid can be squeezed out by puncturing the wall of the cysts with a needle. 2. Lipoma: soft and elastic lumps usually appear under the skin of the wrist, and the tumor usually needs to be surgically removed. Superficial lesions are easier to remove, and deep tumors are difficult to remove completely. 3. Radius fracture: Extension type radius fracture will lead to bone protrusion, forming bayonet-like deformity and raised hard lumps, ibuprofen can be used for pain relief when the pain is severe; surgical treatment can be performed when the manipulative repositioning is unstable, such as percutaneous Kirschner’s pin fixation, incision and repositioning of Kirschner’s pins; it can also be performed through manipulative repositioning to restore the displaced bones to the normal physiological position and promote healing. Raised hard lumps in the joints of the hands may also be related to osteophytes, joint cysts, bone tumors and other factors, and it is recommended that the patient consult a doctor in time for treatment and strictly follow the doctor’s instructions for medication.