Zhi Bai Di Huang Wan and Qi Ju Di Huang Wan are different in composition, efficacy and treatment as well as contraindications. 1. Composition: Zhi Bai Di Huang Wan is made up of Zhi Mu, Huang Bai, Chinese yam, dogwood, ripe ground, danpi, Poria, zedo and other medicinal herbs. Qi Ju Di Huang Wan is a combination of Chinese wolfberry, chrysanthemum, Chinese yam, cornelian cherry, ripe earth, dandelion, poria, ze lagardine and other herbs. 2. Efficacy and Indications: The main effect of Zhi Bai Di Huang Wan is to nourish yin and reduce fire. It is used in treating yin deficiency and fire exuberance, hot flashes and night sweating (sweating abnormally after going to sleep and stopping after waking up), tinnitus and spermatorrhea, dry mouth and sore throat. The main effect of Qi Ju Di Huang Wan is to nourish kidney and liver. It is used for vertigo, tinnitus, astigmatism, photophobia and blurred vision due to deficiency of yin in liver and kidney. 3. Contraindications: Although there are no clear adverse reactions and contraindications, but Zhibai Di Huang Pills pregnant women should be cautious, not applicable to patients with deficiency cold disease, it is advisable to take on an empty stomach or before meals with boiled water or saline solution. Qi Ju Di Huang Wan spleen and stomach cold, loose stools should be used with caution. The composition of the two drugs, efficacy and treatment, as well as the use of contraindications are different. It is recommended that before using the drug, the patient first to the local formal medical institutions, by the doctor according to the condition of their own situation to give advice on the use of medication, and comply with the doctor’s instructions to take the correct medication.