Hands in May and June on the peeling may be associated with exfoliative keratolysis, sweat herpes, contact dermatitis and other factors, you can use medication, avoid hand contact with irritating substances. 1. Exfoliative Keratolysis: hands in May and June on the peeling skin may be suffering from exfoliative Keratolysis, accompanied by sweating symptoms, you can use topical retinoic acid cream, urea cream and other medications, pay attention to rest, relaxation of the mind. 2. Sweat herpes: hands in May and June on the peeling skin may have sweat herpes, with local allergies, mental factors and so on. You can take oral loratadine, cetirizine hydrochloride and other antihistamines, external glucocorticoid cream such as mometasone furoate cream. 3. contact dermatitis: hand to the May-June peeling may be related to contact dermatitis, hand contact with laundry detergent, disinfectant and other irritants or sensitizers caused by the usual remember to keep hands away from the relevant substances, wash hands after the appropriate application of emollient milk to help moisturize the hands, and in severe cases, can be taken orally loratadine and other antihistamines to ease the situation. Hands in May and June on the peeling can go directly to the regular hospital dermatology consultation, by the doctor to guide the use of medication.