Nodular disease causes mediastinal lymph node enlargement, for ordinary nodular disease usually do not need special treatment, symptomatic patients can follow the doctor’s instructions for drug treatment. It is recommended that patients go to regular hospitals to receive further examination and treatment in time to avoid delaying their condition. 1. Ordinary nodal disease: mediastinal lymph node enlargement caused by nodal disease, but there is no other systemic symptoms usually do not need special treatment, the patient can pay attention to regular follow-up, strengthen the rest, appropriate exercise, and enhance the body’s resistance. 2. Symptomatic nodal disease: When mediastinal lymph node enlargement caused by nodal disease is accompanied by neurological and respiratory symptoms, the patient should follow the doctor’s instructions to use prednisone, methotrexate, cyclophosphamide, etc. for treatment. Patients should go to the hospital in a timely manner, after clarifying the condition of the symptomatic treatment, the drug should be used in strict accordance with the doctor’s instructions, do not self-medication, to avoid adverse consequences.