Coronary artery spasms of a few seconds’ duration require attention and early intervention for underlying diseases to prevent progression to serious consequences such as myocardial infarction. Coronary artery spasm is a pathophysiologic condition that can be categorized into different clinical types depending on its location and severity, including variant angina, acute myocardial infarction, arrhythmia, heart failure, etc. It usually leads to recurrent episodes of chest pain and is recommended to be treated as soon as possible. It usually leads to recurrent episodes of chest pain, and it is recommended to consult a doctor as soon as possible for appropriate treatment to relieve it. The cause of coronary artery spasm is not clear, and may be related to long-term smoking and alcohol abuse, lipid metabolism disorders, hyperthyroidism, some drug use, diabetes, hypertension and so on. If the symptoms of coronary artery spasm occur for a few seconds, we should pay attention to them and consult the doctor in time, and then perform ECG and other related examinations to clarify the underlying diseases and then actively treat them so as to avoid their progression. Specific treatment should follow the doctor’s instructions.