Vaccine bivalent quadrivalent and nine-valent, generally refers to the HPV vaccine, the difference between them is mainly the different types of viruses prevented, the applicable age is different, the price is different. 1. Different types of viruses prevented: bivalent vaccine can prevent HPV16 and HPV18 viral infections, quadrivalent vaccine can prevent HPV16, HPV18, HPV6 and HPV11. The quadrivalent vaccine can prevent HPV16, HPV18, HPV6 and HPV11, while the quadrivalent vaccine can prevent HPV6, HPV16, HPV18, HPV6 and HPV58. The quadrivalent vaccine can prevent HPV6, HPV11, HPV6, HPV18 and HPV6. 2. Different ages: Bivalent vaccine and quadrivalent vaccine are suitable for women aged 9 to 45 years old, while the nine-valent vaccine is suitable for younger ones, specifically women aged 16 to 26 years old. 3. Different prices: the bivalent vaccine has the lowest price among the three vaccines, the quadrivalent vaccine has a medium price, and the nine-valent vaccine has a higher price. HPV vaccination can prevent most cervical cancers, and it is recommended that women of the right age choose the appropriate vaccination according to their specific situation.