Right epigastric subcostal pressure pain may be caused by trauma or other diseases such as costochondritis, intercostal neuralgia or hepatitis, cholecystitis and so on. 1. Trauma: If the right epigastric subcostal position is stimulated by trauma, it will lead to local soft tissue damage, subcutaneous capillary rupture, subcutaneous nerve stimulation, inducing pressure pain, redness and swelling of the affected area and other symptoms. 2. Costal chondritis: Costal chondritis is usually caused by chronic strain of the ligaments of the thoracic rib joints and nutritional disorders of the rib cartilage. The patient may have the symptom of right epigastric subcostal pressure pain, and the pain may be dispersed to the back of the shoulder. The local pain may be aggravated when the patient coughs or moves the upper limbs. 3. Intercostal neuralgia: degenerative herniation of thoracic intervertebral discs and thickening of joint capsule ligaments may lead to narrowing and deformation of the nerve channel, which induces intercostal neuralgia, causing patients to experience symptoms of chest pain and subcostal tenderness in the right epigastric region. 4. Other diseases: in addition to the above reasons, right epigastric subcostal pressure pain may also be caused by hepatitis, cholecystitis, gallbladder stones and other diseases. There are various causes of right epigastric subcostal pressure pain, and it is recommended that patients go to the hospital for relevant examinations to find out the cause of the disease.