Azoospermia is an important factor causing male infertility, accounting for 10-15% of male infertility factors. 1. What is azoospermia? Azoospermia refers to 3 or more semen analysis tests and no sperm detected after centrifugation of semen. 2.What are the two types of azoospermia? Azoospermia is divided into two types: obstructive and non-obstructive azoospermia. 3. Can azoospermia not produce its own offspring? For obstructive azoospermia, most of them can have their own offspring through recanalization surgery or in vitro fertilization. For non-obstructive azoospermia patients, many can also have their own offspring through testicular microsperm retrieval technology. 4. What is testicular microsperm retrieval? In 1999, Professor Peter N. Schlegel of Cornell University published the first article on non-obstructive azoospermia patients who can have their own offspring through microscopic sperm retrieval surgery. The doctor can magnify the spermatogenic ducts 20-30 times through an advanced surgical microscope and find the thick and full spermatogenic tubules, which will produce a small amount of mature sperm, and the sperm will be retrieved to produce their own offspring through the second generation IVF technique. Microscopic sperm retrieval is currently the best option for patients with non-obstructive azoospermia to have their own offspring. 5. What is the sperm retrieval rate for different types of non-obstructive azoospermia through microscopic sperm retrieval? According to the latest world literature: Testicular hypospermatogenesis: 73-100% Sperm maturation block: 27-86% Only supporting cell syndrome: 22.5-41% Y chromosome microdeletion with deletion of region c: 50-60% Kerner syndrome (47, XXY): 66% The total sperm retrieval rate of our male team is currently 60%.