Loratadine can be taken with Cephalosporin. Cephalosporin should be described as a cephalosporin, which is an antibiotic used primarily to treat infections caused by sensitive bacteria. Loratadine is a commonly used anti-allergic drug, through competitive inhibition of histamine H1 receptors, inhibit histamine-induced allergic symptoms, no obvious anticholinergic and central inhibition. There are no contraindications for the two drugs. Loratadine is used clinically to relieve symptoms associated with allergic rhinitis, sneezing, runny and itchy nose as well as itching and burning sensation of the eyes. It is also used to relieve symptoms of chronic urticaria and other allergic skin diseases. Loratadine adverse reactions include weakness, headache, drowsiness, dry mouth, and rash. Use with caution in women during pregnancy and in patients with hepatic or renal insufficiency. It is contraindicated for those who are allergic to loratadine and its contained ingredients. Cephalosporin should not be taken by people with a history of penicillin allergy. When using it, it is recommended to consult a pharmacist or doctor for the specific medicine.