Molecular typing of breast cancer

Regarding the molecular typing of breast cancer, it is generally classified clinically as LuminalA, LuminalB, HER2-positive, and also triple-negative breast cancer. LuminalA refers to Er, which means estrogen receptor and progesterone receptor positive, HER2 negative, Ki-67 should be less than the previous standard of 14%, while the current standard is ≤20%, then such a molecular expression is called LuminalA. The Luminal B type, which is estrogen receptor and progesterone receptor positive, and HER2 positive also belongs to Luminal B type. For HER2-positive type, ERPR is negative and HER2 is positive, such a molecular expression is called HER2-positive type. Triple-negative breast cancer means ER is negative, PR is negative, and HER2 is also negative, for such a molecular type, it is usually called triple-negative breast cancer.