The causes of high pituitary prolactin in women can be divided into physiological and pathological causes. The so-called physiological causes are as follows: 1) a large increase in prolactin during pregnancy; 2) a large increase during breastfeeding; and 3) a temporary increase in prolactin due to long-term nipple stimulation. The reason for the pathology is as follows: 1. drug-related, such as long-term consumption of drugs like Gastrofacial may lead to increased prolactin; 2. abnormal hyperplasia of the breast ducts, leading to increased prolactin; 3. tumor lesions of the hypothalamus-pituitary gland also promote the secretion of prolactin hormones. In particular, prolactinomas can themselves show a large increase in prolactin.