Ischemic colitis can be treated with fluids, antibiotics such as cephalosporins, and surgical resection, which usually do not raise platelets, and platelet elevation during treatment may be caused by infection, colitis, and so on. Ischemic colitis is usually caused by mesenteric vascular embolism, infection, and other causes of colonic vascular occlusive ischemia or non-occlusive ischemia, and may have symptoms such as abdominal pain, diarrhea, and blood in the stool. The main treatment during an acute attack is to check vital signs, while fasting and administering fluids, etc. to replenish water and electrolytes. Medications such as ceftriaxone can also be taken to inhibit the growth of germs and actively fight infection. Colon resection can also be performed to remove the ischemic portion of the intestine and restore blood perfusion to the intestinal mucosa. Treatment of ischemic colitis does not usually appear to cause platelet elevation. If there is mesenteric infection, platelet elevation may occur due to the inflammatory response. Platelet elevation may occur if there is ulcerative colitis, intestinal tumors, and other trauma that promotes the release of proplatelet factors. Elevated platelets may also be caused by ischemic anemia and myeloproliferative disorders. If platelet elevation occurs during treatment, excluding ischemic colitis itself caused by inflammatory reaction, the cause should be promptly identified under the guidance of the doctor and actively treated.