After taking progesterone without menstruation, you should first pay attention to observation, go to the hospital for blood and urine HCG and other related tests, if it is a normal phenomenon or pregnancy, there is no need for special treatment, if there is a lack of estrogen, it is recommended to take oral estradiol valerate and dextroprogesterone tablets and other drugs to treat. 1. Normal phenomenon: Generally, menstruation will occur within 3-7 days after stopping progesterone, it is normal not to have menstruation during the period of medication or just after stopping the medication, it is recommended to pay attention to observation. If there is no menstruation after stopping progesterone for a week, it is recommended to go to the hospital in time for examination and symptomatic treatment. 2. Pregnancy: If the patient does not have menstruation for a week or two after stopping progesterone, he should go to the hospital in time to check the blood and urine HCG, ultrasound and other tests, and if he is diagnosed with pregnancy, he does not need to take the drug to avoid harm to the body. 3. Insufficient estrogen: It may be that the estrogen level in the patient’s body is insufficient, so there is a phenomenon that menstruation does not come after taking progesterone drugs. It is recommended that estrogen should be supplemented in time, and under the guidance of the doctor, estradiol valerate tablets, dydrogesterone tablets and other drugs can be taken orally for treatment. It is recommended that patients with physical abnormalities, do not self-medication, should go to the hospital in a timely manner, so as not to cause harm to the body.