Ineffective platelet transfusion means that the patient’s platelet count does not rise as much as one would expect after a platelet transfusion, and there is no significant change in the platelet count. Platelet transfusion is ineffective for two common reasons: the first reason is that repeated platelet transfusion patients, such as patients with aplastic anemia, or leukemia patients after chemotherapy, due to repeated platelet transfusion, because these platelets come from different people, it will stimulate the patient’s body to produce different antibodies, and eventually lead to the production of various antibodies, and then the rejection of the platelets imported into the body The reaction leads to the destruction of platelets. The second common disease, called autoimmune thrombocytopenia, is due to the patient’s own immune dysfunction, producing autoantibodies against platelets, and if platelets are transfused, the autoantibodies will bind to the platelet membrane, resulting in the destruction of platelets in the peripheral circulation and the ineffective transfusion of platelets.