In general, taking H. pylori medication is always hungry considered as drug-induced gastrointestinal reactions, gastrointestinal diseases, endocrine diseases and so on. 1. Drug-induced gastrointestinal reactions: anti-Helicobacter pylori drugs such as clarithromycin, furacilin, amoxicillin, metronidazole, etc., there may be gastrointestinal reactions, such as nausea, vomiting, diarrhea, and hunger, which are the adverse reactions of drugs. 2. Gastrointestinal diseases: patients infected with Helicobacter pylori may have gastrointestinal diseases such as gastric ulcer, chronic gastritis, etc., which can cause gastrointestinal symptoms such as hunger, stomach pain, acid reflux and heartburn. 3. Endocrine diseases: such as hyperthyroidism, diabetes and other diseases, so that the body is in a state of high metabolism, protein, fat and other nutrients decomposition increased, so that the patient produces a sense of hunger, leading to lethargy, polyphagia and other symptoms. Eating Helicobacter pylori medication is always hungry may also be caused by hypoglycemia and other diseases, it is recommended that patients seek medical attention in a timely manner in order to clarify the diagnosis, targeted treatment.